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Each cycle of 110 women with ovulatory menstrual cycle equally devided into eight categories, and devided each cycles, which belong to same category were made in 8 groups. The studies were undertaken about changes in karyo-pyknotic indices of each group and results obtained were summarized as follows. Mean values of each group of karyo-pyknotic indices from group 1 to group 8 were 22.9%, 39.9%, 48.6%, 56.2%, 17.4%, 26.7%, 27.6% 15.0% respectively. Karyo-pyknotic indices observed among the group 1 to the group 4, progrssively increasing tendency and marked decrease at group 5, slight increasing tendency thereafter, the lowest value at group8. Difference of karyo-pyknotic index noted between group 4 and group 5 was significant.
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